KEMA2830 Organic Chemistry 2: Structure and Reactivity (4 cr)

Introduction to carbonyl chemistry. Nucleophilic addition reactions to the carbonyl group. Reduction of carbonyl compounds. Organometallic reagents in carbonyl additions. Carboxylic acid derivatives - reactions via nucleophilic substition. Enolate chemistry: substitution reactions in the α carbon of carbonyl compounds. Carbonyl condensation reactions (Claisen and related condensations). Applications in industrial chemistry and biochemistry, including enzymatic reactions involving carbonyl groups in cellular metabolism.

Working life skills

The course develops students' expression in chemistry and problem solving skills. In exercises are learnt to solve demanding problems both individually and in groups. Homeworks and exercises are scheduled, so the course also teaches how to plan and execute on schedule.

KEMA2820 Organic Chemistry 1: Basic Analysis Methods and Reactions or KEMA282 Organic Chemistry 1 or equivalent knowledge.

• Janice G. Smith: Organic Chemistry (5th Ed.), McGraw-Hill 2016