KEMS5390 Practical NMR Spectroscopy (2 cr)

Study level:
Advanced studies
Grading scale:
Pass - fail
Language:
English, Finnish
Responsible organisation:
Department of Chemistry
Curriculum periods:
2020-2021, 2021-2022, 2022-2023

Description

The course gives an introduction to the principles of nuclear magnetic resonance spectroscopy and its utilization in structural analysis.

  • Basic concepts of NMR spectroscopy
  • Chemical shift and factors influencing on it
  • Spin-spin coupling
  • Sample preparation
  • Measurement and processing of the most common 1D and 2D NMR spectra
  • Spectral interpretation exercises

Learning outcomes

After completing the course the student

  • knows the basic principles and terms related to NMR spectroscopy.
  • understands the physical principles underlying the NMR phenomenon and realizes the possibilities of NMR spectroscopy in analyzing the structures of molecules.
  • knows factors influencing on chemical shifts.
  • is able to analyze first-order coupling patterns.
  • is aware of the principles on NMR sample preparation.
  • knows how to choose the most reasonable NMR experiment(s) for each structural analysis.
  • familiarizes her/himself with measuring NMR spectra.
  • is able to analyze simple 1D and 2D NMR spectra.

Working life skills

  • The student is able to plan and control the use of time related to duties and assignments, and is able to keep up with the agreed schedule.
  • The student can combine and apply the knowledge learned during the course within a broader context.
  • The student knows how to independently search for information and to evaluate its quality and reliability.
  • The student is able to find answers and solutions to the given problems and exercises both orally and literally. The student is able to justify her/his answers.
  • The student can discuss about NMR spectroscopy using the correct terminology.
  • The student knows how to write a report about her/his work.

Additional information

The course replaces the previously lectured course KEMS537: NMR Spectroscopy in Structural Elucidation.

The course will be lectured yearly in the 2. period.

Description of prerequisites

Intermediate studies in Chemistry

Study materials

  • J.H. Simpson, Organic Structure Determination Using 2-D NMR Spectroscopy, 2nd Ed., Academic Press, 2012. Chapters 1, 2 (selected parts), 4-6, 9-10.

Completion methods

Method 1

Evaluation criteria:
In order to complete the course the student needs to select the necessary NMR measurements for solving the structure of an unknown compound and to give a written report of its structural analysis based on the NMR spectra. The structure of the compound has to be correctly analyzed for passing the course.
Time of teaching:
Period 1
Select all marked parts
Parts of the completion methods
x

Teaching (2 cr)

Type:
Participation in teaching
Grading scale:
Pass - fail
Language:
English, Finnish
Study methods:

Written report of the structural analysis of an unknown compound based on the selected NMR experiments. Teaching language is English if needed.

Teaching