KEMS5380 Basics of NMR Spectroscopy (4 cr)

Study level:
Advanced studies
Grading scale:
0-5
Language:
English, Finnish
Responsible organisation:
Department of Chemistry
Curriculum periods:
2020-2021, 2021-2022, 2022-2023, 2023-2024

Description

The aim of this course is to explore nuclear magnetic resonance as a phenomenon and to widely cover factors influencing on chemical shifts. Spin-spin coupling together with the 1D and 2D NMR experiments based on it as well as instrumental considerations, data collection, and processing are introduced at a theoretical level. Additionally, the course covers the basics of dynamic NMR spectroscopy.

  • Construction and principles of the NMR spectrometer
  • Collecting and processing of the FID
  • Factors influencing on chemical shifts
  • Spin-spin coupling
  • The most common 1D and 2D NMR experiments
  • Nuclear Overhauser effect (NOE)
  • Relaxation and dynamic NMR spectroscopy

Learning outcomes

After completing the course the student

  • Knows the basic principles and terms related to NMR spectroscopy.
  • Understands the physical principles underlying the NMR phenomenon and realizes the possibilities of NMR spectroscopy in analyzing the structures of molecules.
  • Is aware of the basic construction and principles of an NMR spectrometer.
  • Is able to process the measured data with an appropriate way.
  • Understands widely the factors influencing on chemical shifts.
  • Is able to recognize and analyze coupling patterns.
  • Understands the principles of the most common 1D and 2D NMR experiments and can apply them in structural analysis.
  • Familiarizes her/himself with nuclear Overhauser effect and dynamic NMR spectroscopy.

Working life skills

  • The student is able to plan and control the use of time related to duties and assignments, and is able to keep up with the agreed schedule.
  • The student can combine and apply the knowledge learned during the course within a broader context.
  • The student knows how to independently search for information and to evaluate its quality and reliability.
  • The student is able to find answers and solutions to the given problems and exercises both orally and literally. The student is able to justify her/his answers.
  • The student can discuss about NMR spectroscopy using the correct terminology.

Additional information

The course replaces the previously lectured course KEMS536: Theoretical Basics of NMR Spectroscopy.

Description of prerequisites

KEMS5390 or corresponding knowledge

Compulsory prerequisites

Study materials

  • J.H. Simpson, Organic Structure Determination Using 2-D NMR Spectroscopy, 2nd Ed., Academic Press, 2012. Chapters 1-8.

Completion methods

Method 1

Evaluation criteria:
Passing the course (1/5) requires at least 50% of the maximum score on the course.
Time of teaching:
Period 3, Period 4
Select all marked parts

Method 2

Evaluation criteria:
Passing the course (1/5) requires at least 50% of the maximum score on the exam.
Select all marked parts
Parts of the completion methods
x

Teaching (4 cr)

Type:
Participation in teaching
Grading scale:
0-5
Language:
English, Finnish
Study methods:

Lectures, exercises, and exam. Teaching language is English if needed.

Teaching

x

Online teaching and exam (4 cr)

Type:
Exam
Grading scale:
0-5
Language:
English, Finnish
Study methods:

If you want to take exam in English, please contact the teacher.

Teaching