213031.0 Computer Aided Drug Design (5 cr)
Cooperation network course
Network: National doctoral courses
Available for: Doctoral studies
This course is offered through the Network for Doctoral Studies. These studies are available for doctoral degree students studying in the University of Jyväskylä.
Network: FINStruct courses in integrative structural biology OY-HY-UEF-TY-ÅA
Grading scale:
0-5
Description
This course gives an understanding of how drugs interact with macromolecules and strategies for how this information can be used in designing novel therapeutics using computational methods. The computational strategies based on the 3D structures of small molecules are also presented. The course contains lectures and computer exercises on ligand-based and structure-based drug design, drug-protein interactions, ligand docking, conformational analysis, pharmacophore hypothesis and quantitative structure-activity relationship.
Learning outcomes
Learning Outcomes:
After taking the course, the student is expected to be able to
-describe computer aided drug design strategies in overall
-perform computer exercises related to computer-aided drug design according to the given instructions
-perform and report a project work related to computer-aided drug design
Transferable skills:
During the course the participant develop the following general skills:
- theoretical knowledge on computer aided drug design strategies
- information retrieval skills
- ability to learn and adopt new things
- project management and co-operation skills
- ITC skills
- communication in English
Description of prerequisites
Requires basic knowledge on biomolecules (150 sp of BSc studies).