KEMS5380 Basics of NMR Spectroscopy (4 cr)

The aim of this course is to explore nuclear magnetic resonance as a phenomenon and to widely cover factors influencing on chemical shifts. Spin-spin coupling together with the 1D and 2D NMR experiments based on it as well as instrumental considerations, data collection, and processing are introduced at a theoretical level. Additionally, the course covers the basics of dynamic NMR spectroscopy.

• Construction and principles of the NMR spectrometer
• Collecting and processing of the FID
• Factors influencing on chemical shifts
• Spin-spin coupling
  
• The most common 1D and 2D NMR experiments
  
• Nuclear Overhauser effect (NOE)
• Relaxation and dynamic NMR spectroscopy

After completing the course the student

• Knows the basic principles and terms related to NMR spectroscopy.
  
• Understands the physical principles underlying the NMR phenomenon and realizes the possibilities of NMR spectroscopy in analyzing the structures of molecules.
• Is aware of the basic construction and principles of an NMR spectrometer.
  
• Is able to process the measured data with an appropriate way.
  
• Understands widely the factors influencing on chemical shifts.
  
• Is able to recognize and analyze coupling patterns.
  
• Understands the principles of the most common 1D and 2D NMR experiments and can apply them in structural analysis.
  
• Familiarizes her/himself with nuclear Overhauser effect and dynamic NMR spectroscopy.

Working life skills

• The student is able to plan and control the use of time related to duties and assignments, and is able to keep up with the agreed schedule.
  
• The student can combine and apply the knowledge learned during the course within a broader context.
• The student knows how to independently search for information and to evaluate its quality and reliability.
  
• The student is able to find answers and solutions to the given problems and exercises both orally and literally. The student is able to justify her/his answers.
• The student can discuss about NMR spectroscopy using the correct terminology.

Recommended to be taken in the first year of the Master's studies.

KEMS5390 or corresponding knowledge (Basics of NMR, Interpretation of simple 1D and 2D NMR spectra)

• J.H. Simpson, Organic Structure Determination Using 2-D NMR Spectroscopy, 2nd Ed., Academic Press, 2012, or newer. Chapters 1-8.