KEMA2820 Analytical Methods and Basic Reactions in Organic Chemistry (5 cr)

The course will deepen the understanding of organic chemistry.

Basics of organic analytics: 1H, 13C NMR, IR spectroscopy, and mass spectrometry. 

Reactivity and reaction types: Radical reactions (halogenation, allylic and benzylic halogenation, radical addition), substitution reactions (S_N1 and S_N2), and elimination reactions (E1 and E2). The reactions of aromatic compounds: electrophilic aromatic substitution, nucleophilic aromatic substitution, and reactions of aromatic amines. The substituent effects of benzene: reactivity, impact on acidity and basicity.

Reaction mechanistic thinking and synthesis design.

After completing the course, the student 

• can use organic chemistry concepts and terminology.
• knows the principles of the most common analytical methods in organic chemistry.
• is able to identify functional groups from IR spectra.
• is able to identify simple organic compounds based on their mass, ¹H and ¹³C NMR spectra.
• understands the principles of the reactivity of organic compounds.
• is able to identify and apply the reactions studied to synthesise simple organic compounds.
• understands the principles of reaction mechanisms and is able to describe the reaction pathway via reaction mechanisms.
• is able to design the synthesis of organic compounds based on the reactions learnt during the course.
  

Working life skills: 

• Master planning of their workload and is able to follow the given schedules and deadlines.
• Is able to connect and apply the concepts learnt during the course to a broader chemistry context and to the topics of the other courses.
• Is able to independently acquire additional knowledge and expand the knowledge base.
• Is able to justify and explain their answers literally.
• Is able to discuss organic chemistry phenomena using the correct terminology and concepts.
• understands the significance of organic chemistry and organic compounds for the environment, in biological processes, chemical industry and medicine.

KEMP1140 Basics in Organic Chemistry or equivalent knowledge.

• J.G. Smith: Organic Chemistry, 4. edition or newer.
  
• • 4th and 5th ed: chapters 7-9, 13-15, 18, and 25, suitable parts.
  • 6th and 7th ed.: chapters 7-9, SPA, SPB, SPC, 13, 16 and 23 suitable parts..