KEMS526 Modern Synthetic Organic Chemistry (6 cr)

• synthesis and retrosynthetic analysis
• • different strategies
• • retrosynteettinen analyysi
  • erilaiset retrosynteesistrategiat
• organic reactivity
• protecting and activation strategies
• oxidation and reduction in organic synthesis
• different C=C and C-C coupling methods
• organometallics in synthesis
• stereochemical strategies
• asymmetric synthesis and stereoselection
• • catalytic enantioselective reactions in synthesis
  • stereocontrol and face selectivity in reduction, oxidation, and carbonyl chemistry
  • hydrometallations and hydroborations
  • pericyclic reactions
• examples of strategies in synthesis

The goal of the course is to learn to plan realistic, economical syntheses for organic compounds and to evaluate different synthetic strategies. 

Working life skills

The student

• Manages the planning of work, tasks, and time use and adheres to agreed schedules.
  
• Can combine and apply the lessons learned in the course in different contexts.
• Can independently search literature and compile a synthesis plan in an understandable and proficient oral and written presentation.
• Can answer orally and in writing to problems and questions and can clearly explain their answer or opinion.
• Understands ethical and environmental issues related to the subject of the course and is able to consider their implications and solutions.

Spring term, 3rd period

This course is intended for advanced undergraduate studies in organic chemistry. A solid background in organic reactivity (e.g. KEMS541) is strongly recommended. 

• Wyatt & Warren: Organic Synthesis: Strategy and Control. Wiley 2007.
• Carreira & Kvaerno: Classics in Stereoselective Synthesis. Wiley 2008.