KEMS526 Modern Synthetic Organic Chemistry (6 cr)

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Study level:
Advanced studies
Grading scale:
0-5
Language:
English, Finnish
Responsible organisation:
Department of Chemistry
Curriculum periods:
2017-2018, 2018-2019, 2019-2020

Description

Content

Organic reactivity, C=C- and C-C coupling methods, stereochemical strategies, cyclic and acyclic diastereoselectivity, advanced strategies, key methods of asymmetric and stereoselective synthesis. The course consists of a two-stage seminar that includes planning of a synthetic strategy as well as five home exercises. There is no final exam.

Completion methods

Five problem sets (totaling 50% of the overall score) and a two-stage seminar where the students present a synthesis plan for their chosen target molecule.

Assessment details

The problem sets are graded with a score of 0-10 for each problem.

The synthesis plan of the seminar presentation (only the final version) will be graded using the following criteria:

- the credibility and feasibility of the plan. Are there clearly erroneous steps, or steps which are not clearly justified? (20 p)

- the shortness and originality of the plan. (20 p)

- presentational points. Are the literature citations proper and correct? Are the presentation slides clear? Is the presentation logical? (10 p)

The seminars are public and the grading is also based on the collective evaluation based on collected feedback during the presentation.

Please note that your personal style of presentation is not going to be judged.

A passing grade (1/5) requires 50% of the overall score. Higher grades require higher scores; a linear grading will be used, with a grade 5/5 requiring 85% of the overall score.

Learning outcomes

The goal of the course is to boost the skills of students in the use of modern synthetic methods in the planning of organic syntheses and to provide key tools for critical evaluation of synthetic strategies. The purpose of the seminar is to provide the students an opportunity to draft proposals for synthetic routes in small groups and to learn to evaluate and criticize the synthesis plans in a seminar setting.

Additional information

Spring term, 3rd period

Study materials

Lecture material and the associated literature. In addition, the following textbooks: Wyatt & Warren: Organic Synthesis: Strategy and Control. Wiley 2007. Carreira & Kvaerno: Classics in Stereoselective Synthesis. Wiley 2008.

Literature

  • Carreira & Kvaerno: Classics in Stereoselective Synthesis. Wiley 2008.; ISBN: 978-3-527-32452-1
  • Wyatt & Warren: Organic Synthesis: Strategy and Control. Wiley 2007.; ISBN: 978-0-471-92963-5

Completion methods

Method 1

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Parts of the completion methods
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Teaching (6 cr)

Type:
Participation in teaching
Grading scale:
0-5
Language:
English, Finnish

Teaching