KEMA283 Organic Chemistry 2 (4 cr)

Study level:
Intermediate studies
Grading scale:
0-5
Language:
Finnish
Responsible organisation:
Department of Chemistry
Curriculum periods:
2017-2018, 2018-2019, 2019-2020

Description

Content

Introduction to carbonyl chemistry. Nucleophilic addition reactions to the carbonyl group. Reduction of carbonyl compounds. Organometallic reagents in carbonyl additions. Carboxylic acid derivatives - reactions via nucleophilic substition. Enolate chemistry: substitution reactions in the α carbon of carbonyl compounds. Carbonyl condensation reactions (Claisen and related condensations). Applications in industrial chemistry and biochemistry, including enzymatic reactions involving carbonyl groups in cellular metabolism.

Completion methods

Exercises, problem sets, and final exam.
The course can also be completed by only taking the exam.

Assessment details

Problem sets, e-problems and the exam will be graded and the grade will be based on the total score acquired. Alternatively, the grade can be based on an exam alone.

The problems and the exam will evaluate the students' ability to understand functional group reactivity, different reaction methods, mechanistic thinking, and reaction mechanisms.

A passing grade (1/5) requires 50% of the overall score. Higher grades require higher scores; a linear grading will be used, with a grade 5/5 requiring 90% of the overall score.

Learning outcomes

The goal of the course is to understand the basics of carbonyl-based organic reactivity and the associated mechanistic rationalization of carbonyl reactivity.

Additional information

The course will take place during Period 4 (Spring).

Study materials

Janice G. Smith: Organic Chemistry (5th Ed.), McGraw-Hill 2016

Literature

  • Janice Smith: Organic Chemistry (5th Ed.), McGraw-Hill 2016; ISBN: 9780077189013

Completion methods

Method 1

Select all marked parts

Method 2

Select all marked parts
Parts of the completion methods
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Unpublished assessment item
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Unpublished assessment item